New Drugs for Dementia

October 12, 2016

Source: Parliamentary Office of Science and Technology

Follow this link for fulltext

Date of publication: August 2016

Publication type: Report

In a nutshell: This POSTnote provides an overview of dementia, current treatments and potential new drugs. It examines the challenges involved in developing new drugs and in ensuring patient access. Finally, it considers prevention strategies.

Length of publication: 6 pages


Approved drugs are to be studied for use in Alzheimer’s disease

October 12, 2016

Source: BMJ

Follow this link for fulltext

Date of publication: September 2016

Publication type: Journal article

In a nutshell: “Many drugs that have been approved by the Food and Drug Administration could be repurposed or used off label to treat Alzheimer’s disease, according to reports from the Alzheimer’s Drug Discovery Foundation conference in New Jersey.
The foundation is supporting 18 approved drugs in repurposing trials. This brings the total number of approved drugs that were being studied for use in treating Alzheimer’s disease in repurposing trials to at least 127, the foundation said.”

Length of publication: 1 page

Some important notes: This article is available in full text to all NHS Staff using Athens, for more information about accessing full text follow this link to find your local NHS Library

Audit of antipsychotic prescribing for dementia – falls & rises

September 5, 2012

Source: NHS Information Centre

Follow this link for the full report National Dementia & Antipsychotic Prescribing Audit 2012 and Website

Date of publication: July 2012

Publication type: Report

In a nutshell:  the results showed a 52% decrease in the rate of prescribing between 2008 and 2011. Prescriptions for antipsychotics in people newly diagnosed (diagnosed each year with a prescription of an antipsychotic within 12 months of diagnosis) with dementia have also reduced from 14.25 per cent in 2006 to 4.46 per cent in 2011which indicates that diagnosis is taking place much earlier.

  • The audit shows that over the last six years there has been an increase in the number of people diagnosed with dementia.
  • The audit shows that a higher proportion of women are diagnosed with dementia than men with the majority of people diagnosed with dementia aged 65 years and above.
  • The audit suggests that the proportion of dementia sufferers receiving prescriptions of antipsychotic medication is decreasing.

Length of publication: 28 pages